ExpertCenter D5 Mini Tower (D500MER)
ExpertCenter D5 Mini Tower (D500MER)
- Windows 11 Pro - ASUS recommends Windows 11 Pro for business
- Up to Intel® Core™ i7 14th gen Processor
- 15L compact chassis
- Up to 64 GB DDR5 memory
- Up to 2 TB HDD + 2 TB SSD storage
- MIL-STD 810H durability
- Tool-free chassis design
- Two-way AI noise-canceling
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Outstanding Value for business at any sizes
Engineered specifically for the specific demands of small businesses, the ASUS ExpertCenter D5 Mini Tower boasts powerful, trustworthy, and expandable performance. Its modern, compact, and flexible design caters to diverse workspaces and usage scenarioses. Take advantage of our simplified small-business support services to experience reduced downtime and a more economical total cost of ownership.
Secure manageability
ExpertCenter D5 Mini Tower prioritizes security through TPM 2.01, providing advanced protection with two options: Firmware TPM, a software-based solution running on the CPU, and Discrete TPM, a dedicated chip offering an additional layer of defense against sophisticated threats.
Efficient expandability
The perfect balance of performance and size with remarkable expandability that provides space for essential hardware to support diverse productivity needs.
Tool-free chassis
The redesigned tool-free chassis makes it easier to remove components by hand, simplifying routine servicing and making future upgrades a breeze.
Ultimate reliability
Built with industry-leading ASUS motherboards and tested to stringent ASUS and MIL-STD 810H US military standards2, minimizing risk of damage and maximizing longevity.
Exceptional performance, whatever the task
To make light work of all your business tasks, ExpertCenter D5 Mini Tower is powered by the latest Intel® Core™ 14th gen processor with up to 64 GB DDR5 RAM. An NVIDIA® discrete GPU is an option for those requiring advanced graphics performance for demanding visual tasks.

Copilot in Windows
Copilot4 in Windows with commercial data protection is your Al assistant at work. Supercharge your productivity and achieve more with less time and effort using Copilot. Experience your everyday Al companion now with the dedicated Copilot key. Just one click for endless exploration.

Maximize your workspace
ExpertCenter D5 Mini Tower is 42%5 smaller than a traditional tower PC, helping to maximize your office workspace. And its sleek and elegant design gives your business a truly professional look — ready to work in style.
Hassle-free maintenance and upgrades
ExpertCenter D5 Mini Tower has a redesigned tool-free chassis. The removable HDD cage offers more accessibility to the motherboard, and the ODD also comes off easily, making component upgrades and routine servicing easy.
Power to do more
To adapt seamlessly to your business workflow, ExpertCenter D5 Mini Tower features a full array of expansion capabilities, including flexible back I/O ports, storage, graphics and WiFi. It’s easy to configure for all your current and future demands.
Less heat, more productivity
To ensure stable performance, ExpertCenter D5 Mini Tower employs an innovative multi-channel cooling system. ExpertCenter D5 Mini Tower also incorporates the exclusive MyASUS6 app to optimize the operation of the CPU and system fans, automatically moderating the speeds and switching them off completely when possible, striking the perfect balance between maximum performance and minimum noise.
AI noise-canceling audio technology for business
To level up professional conferencing, ExpertCenter D5 Mini Tower has two-way AI noise-canceling technology7 that employs sophisticated machine-learning techniques. The technology includes both an upstream function to filter noise around the speaker, and a downstream function to eliminate noise from the person at the other end of the conversation. Try the demo to experience the amazing difference that ASUS two-way AI noise-canceling technology can make.
Turn on your device’s audio and press play to experience AI noise-canceling technology.






Ready for the business world
A full array of I/O ports is ready to connect ExpertCenter D5 Mini Tower to a wide range of business peripherals. It has four front-mounted USB ports for quick and easy access and flexible serial and parallel ports on chassis leave more PCI Express® slots available for additional upgrades. A smart-card reader and an optional SD card reader for easy transactions, data transfer, or other business-related tasks.


b) Copilot in Windows (in preview) is rolling out gradually within the latest update to Windows 11 in select global markets. Timing of availability varies by device and market. Learn more: http://www.microsoft.com/en-us/windows/copilot-ai-features?r=1#faq
c) Copilot with commercial data protection requires Microsoft 365 E3, E5, Business Standard, Business Premium or A3 or A5 for faculty, or accessed using Microsoft Entra ID.